Parasym Plus Ingredients

Four ingredients. Five patents. Eight years of research by Dr. Diana Driscoll. Learn what goes into Parasym Plus and why the specific formula matters more than any single ingredient on its own.

Supplement Facts

Serving Size: 2 Capsules Servings Per Container: 30
Amount Per Serving % Daily Value
Thiamine Hydrochloride (Vitamin B1) 60 mg 5,000%
Proprietary Blend 740 mg
Alpha-Glyceryl Phosphoryl Choline
Acetyl-L-Carnitine
Huperzia serrata leaf standardized extract

† Daily Value (DV) not established.

Other ingredients: Magnesium stearate, vegetable capsule.
Does not contain gluten, corn, salt, sucrose, starch, nuts, yeast, artificial colors or flavors. May contain soy.
5 U.S. Patents
Made in USA
GMP Certified
60-Day Guarantee

How Each Ingredient Supports Your Vagus Nerve

Parasym Plus works by doing three things at once: providing the raw material for acetylcholine, supporting its synthesis, and slowing down its breakdown. No other supplement takes this approach. That is why the formula is patented.

Thiamine (Vitamin B1)

60 mg per serving

Most people think of B1 as just an energy vitamin. And it does help convert food into usable cellular energy. But B1 also plays a critical role in producing acetylcholine, the neurotransmitter your vagus nerve runs on. We include it at 60mg because many people with vagus nerve concerns turn out to be low in B vitamins without even realizing it.

  • Supports natural energy production
  • Essential for healthy nerve signaling
  • Helps your body produce acetylcholine
  • Supports mental clarity and focus

Alpha-GPC

In proprietary blend

Alpha-GPC is one of the most bioavailable forms of choline you can take. Unlike regular choline supplements, it actually crosses the blood-brain barrier. That means it reaches your brain and nervous system directly, where your body converts it into acetylcholine. This is the raw material your vagus nerve needs to function. Learn what happens when acetylcholine runs low.

  • Crosses the blood-brain barrier
  • Directly supports acetylcholine production
  • Promotes memory and mental clarity
  • Supports healthy vagus nerve signaling

Acetyl-L-Carnitine (ALCAR)

In proprietary blend

ALCAR does two things at once in this formula. It shuttles fatty acids into your mitochondria to support sustained energy throughout the day. And it donates its acetyl group to help your body synthesize acetylcholine. Research also shows ALCAR has neuroprotective properties that support brain health as you age. It works hand-in-hand with Alpha-GPC, which is why we included both.

  • Supports healthy cellular energy
  • Neuroprotective properties
  • Aids acetylcholine synthesis
  • Promotes mental sharpness

Huperzine A

In proprietary blend

This is the piece that makes the formula different from anything else on the market. Huperzine A (from Chinese club moss) naturally slows down the enzyme that breaks acetylcholine apart. So while Alpha-GPC and ALCAR help your body produce more acetylcholine, Huperzine A helps it stick around longer. That combination is what the patents protect, and it is why you cannot recreate this formula by buying individual ingredients off the shelf.

  • Preserves acetylcholine levels
  • Extends vagus nerve support throughout the day
  • Supports memory and recall
  • Promotes sustained mental clarity

Try It Risk-Free for 60 Days

If Parasym Plus doesn't make a noticeable difference for you, we will refund your purchase. No questions asked.

Why the Formula Matters More Than the Ingredients

Let's be straightforward. You can find Alpha-GPC, ALCAR, and Huperzine A online. They are not rare or hard to get. So why does Parasym Plus exist?

Because the ingredients alone are not the product. The specific ratios are the product.

Dr. Diana Driscoll spent eight years testing different combinations of these ingredients after her own family faced serious health challenges related to vagus nerve dysfunction. She found that simply taking choline was not enough. Your body also needs help converting that choline into acetylcholine, and it needs help keeping acetylcholine around long enough to actually do its job.

Getting those ratios right took years. Dozens of combinations were tested before she landed on the one that produced consistent, repeatable results. That specific formula is now protected by five U.S. patents.

When you buy these ingredients separately, you are guessing at the ratios. You are also giving up third-party testing, GMP-certified manufacturing, and our 60-day money-back guarantee. We have seen plenty of people try to piece it together on their own. Many of them end up coming back.

More about the science: Top Symptoms of Low Acetylcholine | The Vagus Nerve and Digestion | Frequently Asked Questions

See What Proper Vagus Nerve Support Feels Like

Thousands of people take Parasym Plus every day for digestion, mental clarity, and overall balance. Try it yourself with our 60-day money-back guarantee. If it does not work for you, you do not pay.

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Parasym Plus supplement bottle

Frequently Asked Questions

Can I just buy these ingredients separately?

You can. All three ingredients in the proprietary blend are available individually online. But the specific ratios are what make this formula work. Dr. Driscoll tested dozens of combinations over eight years before arriving at the one that consistently supported vagus nerve function. That formula is now protected by five U.S. patents.

When you buy ingredients separately, you are guessing at those ratios. You are also missing third-party testing, GMP-certified manufacturing, and a 60-day money-back guarantee.

Why is it a proprietary blend?

The specific ratios of ingredients in Parasym Plus are what make it work, and those ratios are protected by five U.S. patents. Dr. Driscoll spent years testing different combinations before finding the one that consistently supported vagus nerve function. The proprietary blend protects that work.

What makes Parasym Plus different from a regular choline supplement?

Most choline supplements give you one thing: choline. That is fine if all you need is more choline. But if you are trying to support your vagus nerve, you need more than raw material. You need your body to actually convert that choline into acetylcholine, and you need it to last long enough to do its job.

Parasym Plus handles all three steps. Alpha-GPC provides the choline. ALCAR and Thiamine support the conversion. And Huperzine A slows down the enzyme that breaks acetylcholine apart. That combination is what the five patents cover.

Is Parasym Plus safe for sensitive individuals?

All ingredients in Parasym Plus are Generally Recognized as Safe (GRAS) by the FDA. The formula does not contain gluten, corn, salt, sucrose, starch, nuts, yeast, artificial colors or flavors. If you have specific concerns, please talk to your healthcare practitioner.

Does Parasym Plus contain soy?

Alpha-GPC is derived from soy lecithin, but our testing (PCR analysis by Genetic ID) does not detect soy DNA at any level. Due to FDA labeling requirements (FALCPA), we include "may contain soy" on the label. Most soy-sensitive individuals tolerate Parasym Plus without issues.

Why is the Vitamin B1 percentage so high (5,000%)?

Thiamine (B1) is water-soluble, meaning your body uses what it needs and passes the rest. It does not build up to toxic levels. The 60mg dose is included because research shows higher amounts are needed to properly support acetylcholine production and nervous system function. Many people with vagus nerve concerns are low in B vitamins without knowing it.

What form of Vitamin B1 is used?

We use Thiamine Hydrochloride, the most widely studied and stable form of Vitamin B1. It is included at 60mg per serving to support acetylcholine production and nervous system function.

How should I take Parasym Plus?

For best results, take 2-3 capsules first thing in the morning on an empty stomach. If you want to add a second dose, early afternoon works well. We do not recommend taking it after about 4pm because the boost in mental clarity can make it harder to fall asleep.

Can I take Parasym Plus with other supplements?

Parasym Plus works best on a basically empty stomach, but it can be taken alongside other supplements. If you are taking medications that affect acetylcholine or the nervous system, check with your healthcare provider first. If you are already taking a choline supplement, you may want to reduce that dose since Parasym Plus contains Alpha-GPC.

Is Parasym Plus vegetarian or vegan?

Yes. Parasym Plus uses vegetable capsules and contains no animal-derived ingredients. It is suitable for both vegetarians and vegans.